IndraLab

Statements

USP10 binds CAPRIN1. 2 / 2
| 2
sparser
"The crystal structures of the nuclear transport factor 2-like (NTF2L) domain of G3BP1 in complex with the G3BP1-interacting motif (GIM) of Caprin-1 and USP10 show that both GIMs bind to the same hydrophobic pocket of G3BP1."
36279435
sparser
"These are the same domains that are necessary for the formation of SGs under conditions of cellular stress, the NTF2-like domain is needed for homodimerisation as well as binding to caprin-1 and USP10, the positive and negative regulators of SGs, while the RGG region mediates binding to the 40S ribosomal subunits [ xref ]."
31199850