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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

HDAC binds HDAC4 and MEF2C. 1 / 1

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"In particular, one of these mechanisms involves a dynamic regulation of the interaction between MEF2C and the transcriptional co-repressors class IIa histone deacetylases (HDACs) such as HDAC4 and −5: in proliferating myoblasts MEF2C interacts with HDACs and its activity is repressed, and myogenic signals disrupt this interaction, thereby alleviating the repression of MEF2C activity xref xref xref xref xref ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...