Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Binding inhibits ATXN3. 1 / 1

| 1

➶

eidos

"Zhou and colleagues found that the small ubiquitin-like modifier-1 ( SUMO-1 ) stablized mutant ataxin-3 through K166 binding and thereby increased neurotoxicity [ 72 ] , while Hwang and Lee reported that SUMO-1 binding promotes degradation of ataxin-3 with polyglutamine expansion through enhanced autophagy [ 73 ] ."

32357546

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...