IndraLab

Statements

Pan3S binds PAN2. 2 / 2
| 2
sparser
"On the other hand, knocking down Pan3L reduced the overall intensity of both peaks 1 and 2 ( xref E, cf. lanes 1 and 4), consistent with the idea that Pan2–Pan3S complex may digest the poly(A) tails all the way through to increase overall deadenylation."
28559491
sparser
"We propose that the first phase of deadenylation, involving differential actions of Pan2–Pan3S and Pan2–Pan3L, represents a previously unsuspected step of mRNA “maturation” in the cytoplasm, with the potential to modulate critical mRNP remodeling and influence the cytoplasmic fate of mRNA."
28559491