IndraLab

Statements

AADAC leads to the methylation of CDKN2A. 3 / 3
| 3
reach
"To further understand how DAC causes hypomethylation of the p16 INK4A and XAF1 genes we examined the status of DNA methyl transferase (DNMT) isozymes which are known to catalyze DNA methylation."
19732952
reach
"Combination treatment of ATRA and DAC induced DNA hypomethylation as well as gene expression of p16 and RARbeta, which contributed to the growth inhibition, differentiation, apoptosis and cell cycle arrest of U937 cells."
30111392
reach
"In spite of CDKN2A hypomethylation induced by DAC, there was n't any change in the expression level of the gene (XREF_FIG)."
22076154