IndraLab

Statements


BRCC3 inhibits NUMA1. 1 / 2
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reach
"However, in BRCC36 silenced cells, a large proportion of NuMA aggregates was retained in the peripheral areas distant from the spindle poles (XREF_FIG; 25-30 min), and supernumerary poles were formed, indicating that depletion of BRCC36 decreases the incorporation of NuMA into spindle poles during mitosis, presumably by aberrant dynamic interaction between NuMA and its partner dynein."