IndraLab

Statements


FOXO activates KCNH3. 3 / 3
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"To further corroborate the notion that bec-1 and beclin1 acts independently of daf-16 and FOXO, we analyzed a daf-16 (mgDf47); bec-1 (ok691) double mutant, and found that complete loss of daf-16 and FOXO also failed to suppress the bec-1 and beclin1 mutant phenotype (XREF_FIG)."

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"To further corroborate the notion that bec-1 and beclin1 acts independently of daf-16 and FOXO, we analyzed a daf-16 (mgDf47); bec-1 (ok691) double mutant and found that complete loss of daf-16 and FO[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Whether bec-1 and lgg-1 are directly activated by FOXO and DAF -16 in worms is unknown, but both genes are transcriptionally activated by FOXO in mammals."