IndraLab

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USP35 increases the amount of CPC proteins. 1 / 1
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"Indeed, USP35 knockdown could not disrupt the levels of other CPC proteins, such as INCENP or Survivin, indicating that USP35 does not affect other CPC proteins and may only have an effect on Aurora B. Based on these data, we concluded that USP35 induced deubiquitination of Aurora B could affect its downstream signaling, which is required for faithful mitotic progression."