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ADIPOQ increases the amount of USP2. 5 / 5
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"It would be interesting to examine the role of AMPK and JAK and STAT signaling in the modulation of USP-2 expression by adiponectin and leptin for the future study.Cyclin D1, an important regulator of[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Although USP-2 seems to play a critical role in USP-2 expression modulated by adiponectin and leptin, the only little information regarding molecular mechanisms underlying USP-2 expression is availabl[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Herein, we present the evidence that changes in USP-2 expression by adiponectin and leptin contribute to the regulation of cyclin D1 degradation by proteasomes that impacts cell cycle modulation in ca[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In the present study, we clearly demonstrated that adiponectin and leptin modulates expression of USP-2 expression in the opposite manner, which in turn directly impacts cyclin D1 degradation (Figs. 3[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"As expected from our microarray data, adiponectin did not trigger elevated transcript levels of TR2, CASP1 and USP2 in MCF-7 breast cancer cells, but a significantly reduced USP2 expression by approximately 60%."
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