IndraLab

Statements

SKP2 binds USP10. 6 / 6
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"By further mapping the regions of USP10, we showed that the N-terminal region (1-205aa) was required for the binding of USP10 to SKP2."
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"Mechanically, USP10 can bind to Skp2 and stabilize its protein level by removing polyubiquitin on Skp2 in the cytoplasm."
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"We also validated the interaction between exogenous USP10 and SKP2 using Co-IP in HEK293 cells that were co-transfected with FLAG-USP10, FLAG-USP13, and HA-SKP2 plasmids."
31044085
sparser
"Mechanically, USP10 can bind to Skp2 and stabilize its protein level by removing polyubiquitin on Skp2 in the cytoplasm."
34599966
sparser
"By further mapping the regions of USP10, we showed that the N-terminal region (1-205aa) was required for the binding of USP10 to SKP2 (Fig.  xref )."
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"We found that SKP2 interacted with USP10, USP13, UCHL5, USP14, and USP7 in KBM5-T315I cells."
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