IndraLab

Statements

RARB methylates CDKN2A. 4 / 4
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"Methylation frequency was significantly higher in NAF than adjacent normal tissue for p16 and marginally higher for RAR-β , suggesting that the assessment of p16 and perhaps RAR-β methylation levels in NAF may provide information on whether a breast contains cancer."
19618401
reach
"Treatment of human esophageal cancer cells with 5–50 μM of EGCG for 12–144 h caused a concentration- and time-dependent reversal of hypermethylation of p16 INK4a , retinoic acid receptor beta (RARβ), [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
16563357
reach
"In our study, we found no association between one-carbon nutrients intake and likelihood of gene promoter methylation for E- cadherin, p16 or RAR-beta 2 in breast tumors or any indication of more than additive interaction for folate and alcohol for E- cadherin promoter methylation."
21916701
reach
"Frequent methylation of the cyclin-dependent kinase inhibitor 4A ( p16 INK4a ), Ras-association domain family 1 ( RASSF1A ), H-cadherin ( CDH13 ), retinoic acid receptor-beta ( RARβ ), and cyclin D2 ([MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21757291