IndraLab

Statements

APC Cdh1 inhibits USP1. 3 / 3
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"APC Cdh1 antagonizes USP1 in response to replication stress."
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"More importantly, the depletion of USP1 restored the reduction in HDR efficiency caused by compromised Cdh1 function, reinforcing the notion that APC Cdh1 antagonizes USP1."
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"When USP1 is degraded by APC Cdh1, cells use the HR pathway of DNA repair, and conversely cells would use the NHEJ pathway XREF_BIBR."
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