IndraLab

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KCNMA1 activates KCN. 16 / 16
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"Olesen S-P, Mathiasen D, Christophersen P, Ahring PK, Johansen TE : Kaczorowski GJ, Garcia ML : The p subunit of the high conductance The substituted diphenylurea NS 1608 activates the u-subunit of ca[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
10419851
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"Since Cacna1d encodes a subunit for the calcium channel Caᵥ1.3, and Kcnma1 encodes a calcium-activated potassium channel alpha-subunit [53,54], their dysregulation potentially explains the decreased performance on spatial memory tasks and decreased responsiveness of recorded N-methyl-d-aspartate (NMDA) receptors in adult Mbnl2-null mice."
33077405
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"Finally, we show that NALCN and SLO2.1 are in spatial proximity in MSMC membranes.The functional coupling of SL O 2.1 K+ currents to Na inward currents suggest a highly specialized relationship between SLO2.1 and NALCN channels, resembling the colocalization between calcium channels and the Slo1 calcium-activated potassium channel (BK) (Marrion and Tavalin, 1998)."
34746693
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"These results indicated that the downregulation of KCNMA1 caused aging in auditory hair cells by inducing ferroptosis.There are two broad categories of potassium channels activated by calcium: small c[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
38056217
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"We show that DYSC is expressed in major neuronal tracts and regulates expression of the calcium activated potassium channel SLOWPOKE (SLO), an ion channel also required in the circadian output pathway."
22532808
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"IbTx is considered to be a specific BK channel blocker, whereas ChTx blocks other potassium channels as well as BK channels [30] ."
20974108
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"In parasitic nematodes, EMO interferes with latrophilin receptors (6, 7) and SLO-1 calcium-activated potassium channels (8), leading to paralysis of the pharynx and body-wall muscles, and finally resulting in inhibition of locomotion, feeding, and egg-laying (7, 9, 10)."
31555677
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"KCNMA1 encodes large-conductance Ca 2+ and voltage-activated K + potassium channel α-subunit, which is expressed in the brain and muscles, and regulates the activation and inhibition of neurons and th[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
37977542
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"The functional coupling of I KNa to I NaP that we observe at the single channel level in isolated outside-out patches suggests a highly specialized relationship between K Na and Na V channels perhaps similar to the co-localization between calcium channels and the Slo1 calcium activated potassium channel (BK)."
22357855
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"Syntaxin-1A binds to and modulates the Slo calcium activated potassium channel via an interaction that excludes syntaxin binding to calcium channels."
15496493
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"HSlo α subunit human large conductance calcium-activated potassium channels (Accession no."
15649626
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"The Kcnma1 gene encodes the large conductance calcium-activated potassium channels (BKCa), which are critical for treating various cardiovascular, muscular, and nervous system disorders."
40235541
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"Bellono et al. performed a transcriptomic analysis of skate ampullae and assembled cDNA sequences for highly expressed CaV 1.3 (cacna1d) voltage-gated calcium channels and BK (kcnma1) calcium-activated potassium channels [12]."
37681857
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"11 The link between the vasoconstrictive potency of BOXes and the considerable relevance of Slo1 BK Ca channels in the regulation of vascular tone supported the idea that BOXes may influence the gating properties of this potassium channel."
25169792
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"KCNMA1 encodes the large conductance calcium-activated potassium channel, also known as the BK or K 1.1 channel."
35757096
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"This is the calcium activated potassium channel Slowpoke (SLO) that is known to be regulated by a binding partner, the SLO binding protein (SLOB)."
24062693