IndraLab

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KCNMA1 activates KCN. 8 / 8
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"Syntaxin-1A binds to and modulates the Slo calcium activated potassium channel via an interaction that excludes syntaxin binding to calcium channels."

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"11 The link between the vasoconstrictive potency of BOXes and the considerable relevance of Slo1 BK Ca channels in the regulation of vascular tone supported the idea that BOXes may influence the gating properties of this potassium channel."

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"The functional coupling of I KNa to I NaP that we observe at the single channel level in isolated outside-out patches suggests a highly specialized relationship between K Na and Na V channels perhaps similar to the co-localization between calcium channels and the Slo1 calcium activated potassium channel (BK)."

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"In parasitic nematodes, EMO interferes with latrophilin receptors (6, 7) and SLO-1 calcium-activated potassium channels (8), leading to paralysis of the pharynx and body-wall muscles, and finally resulting in inhibition of locomotion, feeding, and egg-laying (7, 9, 10)."

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"Since Cacna1d encodes a subunit for the calcium channel Caᵥ1.3, and Kcnma1 encodes a calcium-activated potassium channel alpha-subunit [53,54], their dysregulation potentially explains the decreased performance on spatial memory tasks and decreased responsiveness of recorded N-methyl-d-aspartate (NMDA) receptors in adult Mbnl2-null mice."

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"Olesen S-P, Mathiasen D, Christophersen P, Ahring PK, Johansen TE : Kaczorowski GJ, Garcia ML : The p subunit of the high conductance The substituted diphenylurea NS 1608 activates the u-subunit of ca[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"This is the calcium activated potassium channel Slowpoke (SLO) that is known to be regulated by a binding partner, the SLO binding protein (SLOB)."

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"We show that DYSC is expressed in major neuronal tracts and regulates expression of the calcium activated potassium channel SLOWPOKE (SLO), an ion channel also required in the circadian output pathway."