IndraLab

Statements


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sparser
"Taken together, our results demonstrate that USP10 interacts with HDAC7 and stabilize HDAC7 protein through promoting HDAC7 deubiquitination."

sparser
"Next, to gain more insight into the USP10-HDAC7 interaction, a series of GST-tagged truncated mutants of USP10 and HA-tagged HDAC7 were co-transfected, and the C-terminal region (701–798 aa) of USP10 was determined as the binding region with HDAC7 (Fig.  xref f, g)."

sparser
"Therefore, promotion of USP10-HDAC7 axis drives ESCC cell growth."

sparser
"After screening the potential deubiquitinating enzymes of HDAC7, we first reported deubiquitinase USP10 could bind and stabilize HDAC7 protein in ESCC cells."

reach
"Furthermore, deubiquitinase USP10 interacted with and stabilized HDAC7."