IndraLab

Statements


USP21 inhibits HIV-1. 2 / 2
| 2

eidos
"Here , we demonstrate that the deubiquitinase , USP21 , potently inhibits HIV-1 production by indirectly downregulating the expression of HIV-1 trans-activator of transcription ( Tat ) , which is essential for transcriptional elongation in HIV-1 ."

eidos
"Here , we screened a series of USP members and found that USP21 inhibits HIV-1 production by specifically targeting Tat , but not the other HIV-1 accessory proteins ."