IndraLab

Statements

EGFR activates IRS1. 4 / 4
| 4
reach
"Moreover, inhibition of PKA and CAMKII decreased EGF-induced activation of EGFR and AKT and heregulin-induced activation of Her3, IRS1, and AKT."
36332175
reach
"Since Pak1 signaling is also affected EGFR and Akt (a target of IRS1), we next examined the levels of EGFR and IRS-1 proteins in the cell lysates used above in this study."
18922890
reach
"A potential explanation for these results is provided by in vitro data demonstrating that IRS-1 can be targeted by the EGFR."
20670944
reach
"The results of their study demonstrated that miRNA-7 directly suppresses EGFR and upstream modulators of the IGF-1R/Akt signaling pathway, IRS-1 and IRS-2 proteins.Further studies have shown that miRNA-7 has the potential to enhance the sensitivity of the cancer cells to the various therapies."
32592373
Kinase-active EGFR activates IRS1. 1 / 1
1 |
bel
"Modified assertion"
12138086
EGFR bound to INS activates IRS1. 1 / 1
| 1
reach
"50 Insulin, EGF, and other hormone and growth factors activate PI3K and AKT pathway by binding to the insulin receptor or EGFR, and then activate the signaling transducer IRS1."
27819676
EGFR bound to EGF activates IRS1. 1 / 1
| 1
reach
"50 Insulin, EGF, and other hormone and growth factors activate PI3K and AKT pathway by binding to the insulin receptor or EGFR, and then activate the signaling transducer IRS1."
27819676