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IndraLab

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phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
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EGF increases the amount of EGF. 8 / 35
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"The immunofluorescence staining of EGF in mice corneal epithelium showed that the immunofluorescence luminance of EGF in diabetic group were weaker than normal group and netrin-1 treatment can effectively increase the expression of EGF in diabetic mice."
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"The addition of exogenous EGF treatment after the onset of sepsis further augmented intestinal EGF mRNA levels to 2.5 times greater than sham mice (XREF_FIG)."
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"Indeed, EGF levels in the brain were increased by EGF treatment, however to a lesser extent than in the plasma."
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"EGF Treatment Upregulates EGF Expression in MED Rats."
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"In conclusion, EGF may accelerate the healing of DFU, and exogenous EGF treatment may upregulate the expression of EGF mRNA in newly generated tissues."
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"Animals fed the EGF deficient diet RMS had markedly increased EGF and TGF-alpha mRNA levels in duodenum and ileum compared with dam fed controls and significantly elevated total intestinal content of TGF-alpha peptide."
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"Epidermal growth factor (EGF) is synthesized in the pancreas and diabetic animals have low levels of EGF."
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"EGF administration increased levels of crypt proliferation, as alcohol+ EGF mice had higher levels of S-phase cells than alcohol mice; however, EGF was unable to restore crypt proliferation in alcohol+ EGF levels to levels seen in water mice."
EGF bound to EGFR increases the amount of EGF bound to EGFR and GRB2. 1 / 1
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bel
"In the present study the function of Ash/Grb-2 was investigated by microinjecting cells with an anti-Ash antibody. The antibody abolished both S phase entry and the reorganization of actin assembly to ruffle formation upon stimulation with epidermal growth factor (EGF) and platelet-derived growth factor (PDGF). On the other hand, anti-Ash antibody had no effect on S phase entry or actin stress fiber formation induced by either serum or lysophosphatidic acid. Since the induction of DNA synthesis, ruffle induction and stress fiber formation involve a function of Ras, Rac activation and Rho activation respectively, the findings strongly suggest that Ash plays a critical role in the signaling of both pathways downstream from growth factor receptors to Ras and Rac. Consistent with this, Ash co-precipitated with EGF receptor from EGF-stimulated cells."
Modified EGF increases the amount of EGF. 1 / 1
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"The presence of the tumor promoter increased the amount of EGF bound to mammary cells in culture and also decreased a loss in the amount of EGF in the culture medium."
EGF bound to EGFR increases the amount of EGF bound to EGFR and RASA1. 1 / 1
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bel
"Phospholipase C gamma 1 (PLC gamma 1) and p21ras guanosine triphosphatase (GTPase) activating protein (GAP) bind to and are phosphorylated by activated growth factor receptors"