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phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach

EGF leads to the phosphorylation of TSC2. 6 / 6
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"Either U0126 or wortmannin (a PI3K inhibitor) could suppress TSC2 phosphorylation by EGF, while treatment with both inhibitors led to a further reduction ( Figure 1 B), suggesting that upon mitogenic [MISSING/INVALID API KEY: limited to 200 char for Elsevier]"
"Moreover, they were able to inhibit the epidermal growth factor induced Akt activation and tuberin phosphorylation."
"EGF induced a rapid phosphorylation of Akt, tuberin, p70S6K and 4E-BP1 ( xref )."
"Epidermal growth factor can similarly induce tuberin phosphorylation and degradation via a PI3K and Akt pathway in PC-12 cells, but these responses were insensitive to pertussis toxin treatment."
"This subcellular redistribution of active RSK1 is manifested by increased phosphorylation of its cytosolic substrates tuberous sclerosis complex 2 and BAD by epidermal growth factor along with decreased cellular apoptosis."
"EGF induced a rapid phosphorylation of Akt, tuberin, p70S6K and 4E-BP1 (XREF_FIG)."
EGF leads to the phosphorylation of TSC2 on S1798. 1 / 1
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"We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database"