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IndraLab

Statements

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phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

EGF leads to the phosphorylation of TSC2. 6 / 6
| 3 3
sparser
"Either U0126 or wortmannin (a PI3K inhibitor) could suppress TSC2 phosphorylation by EGF, while treatment with both inhibitors led to a further reduction ( Figure 1 B), suggesting that upon mitogenic [MISSING/INVALID API KEY: limited to 200 char for Elsevier]"
reach
"Moreover, they were able to inhibit the epidermal growth factor induced Akt activation and tuberin phosphorylation."
sparser
"EGF induced a rapid phosphorylation of Akt, tuberin, p70S6K and 4E-BP1 ( xref )."
reach
"Epidermal growth factor can similarly induce tuberin phosphorylation and degradation via a PI3K and Akt pathway in PC-12 cells, but these responses were insensitive to pertussis toxin treatment."
sparser
"This subcellular redistribution of active RSK1 is manifested by increased phosphorylation of its cytosolic substrates tuberous sclerosis complex 2 and BAD by epidermal growth factor along with decreased cellular apoptosis."
reach
"EGF induced a rapid phosphorylation of Akt, tuberin, p70S6K and 4E-BP1 (XREF_FIG)."
EGF leads to the phosphorylation of TSC2 on S1798. 1 / 1
1 |
bel
"We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database"