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IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
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EGF phosphorylates RPS6. 10 / 27
| 12 15
sparser
"IGF-1, EGF and serum stimulated the phosphorylation of Akt and rpS6, while DRAM1 dramatically inhibited the phosphorylation of Akt at Thr 308 and Ser 473 and rpS6 at Ser 235/236 and Ser 240/244 (Fig.  xref d)."
sparser
"Furthermore, IGF-1, EGF and serum induced phosphorylation of Akt and rpS6 were also blocked by LY294002, indicating that rpS6 phosphorylation is under the regulation of PI3K-Akt signalling pathway in HEK293T cells."
reach
"Differential regulation of S6 phosphorylation by insulin and epidermal growth factor in Swiss mouse 3T3 cells : insulin activation of type 1 phosphatase."
reach
"However, EGF fails to stimulate DNA synthesis and is unable to stimulate the phosphorylation of S6 ribosomal protein in cells expressing this receptor mutant."
sparser
"As expected, EGF-induced phosphorylation of AKT, S6K, and S6 was abolished by Gαi1 and Gαi3 double knockouts ( Figure 1c and d )."
reach
"IGF-1, EGF and serum stimulated the phosphorylation of Akt and rpS6, while DRAM1 dramatically inhibited the phosphorylation of Akt at Thr 308 and Ser 473 and rpS6 at Ser 235/236 and Ser 240/244."
sparser
"The stimulation by EGF of in situ S6 phosphorylation was also prevented by genistein."
reach
"Epidermal growth factor stimulates phosphorylation of ribosomal protein S6 in serum starved Swiss 3T3 cells, leading to the formation of highly phosphorylated derivatives containing 4-5 phosphates."
sparser
"BI-D1870 and SL0101 showed no important change in EGF-induced phosphorylation of rpS6 and p70S6K ( Fig. 7 F and G)."
reach
"Treatment of cultured astrocytes with FTI-277 significantly inhibited the EGF dependent increase in S6 kinase phosphorylation (XREF_FIG), suggesting that Rheb participates in mTORC1 activation."
EGF leads to the phosphorylation of RPS6 on S240. 1 / 1
1 |
bel
"We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database"
EGF leads to the phosphorylation of RPS6 on S236. 1 / 1
1 |
bel
"We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database"
EGF leads to the phosphorylation of RPS6 on S235. 1 / 1
1 |
bel
"We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database"