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phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
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TGFB1 leads to the phosphorylation of SMAD2. 10 / 480
5 | 3 9 289 166
sparser
"As shown in xref , TGF-β1 induced Smad2 and Smad3 phosphorylation in NRK52E cells."
sparser
"Moreover, TGF-β1-induced Smad2 and Smad3 phosphorylation was higher in L-ENG + than in WT fibroblasts ( xref )."
sparser
"Neither R(-)efonidipine (10 µM), selective T-type CCB, nor nifedipine (10 µM), selective L-type CCB, efficaciously inhibited both TGF-β1-induced Smad2 phosphorylation and [(3)H]-leucine incorporation."
reach
"In contrast, TGF-beta1 induced increased Smad2 phosphorylation in HPMCs (p < 0.001), and pretreatment with> = 0.1 nM of eribulin significantly decreased this effect (0.05 nM p = 0.22, 0.1 nM p = 0.04, 0.5 nM p = 0.01, 1 nM p = 0.009; XREF_FIG)."
sparser
"However, inhibition of Wnt activity did not affect Smad reporter activation and Smad2 phosphorylation induced by RSPO1 or TGFβ1 ( xref )."
sparser
"IL-15SA/IL-15RA did not decrease the TGF-β1-induced phosphorylation of Smad2 or Smad3 ( xref )."
reach
"TGF-beta1 treatment also induced phosphorylation of Smad2 and Smad3 and up-regulation of ALK5 protein, TIMP-1, and alpha2 type 1 collagen gene expression in isolated myofibroblasts."
sparser
"Consistent with previous reports, we found that TGF-β1 increased the phosphorylation of Smad2 as well as the ECM and α-SMA expression in HIFs."
reach
"In contrast, native TGF-beta1 induced only transient Smad2 phosphorylation for only one day, suggesting that pathway activation is critically dependent on TGF-beta1 presentation."
sparser
"Concurrently, SB431542 effectively suppressed TGF-β1-induced SMAD2 phosphorylation in BV-2 microglia (Fig. xref )."
TGFB1 phosphorylates SMAD2 on S255. 1 / 1
| 1
rlimsp
"TGF-β1 phosphorylated Smad2 on the non-receptor substrate sites (Ser245/250/255)."
Modified TGFB1 leads to the phosphorylation of SMAD2. 1 / 1
| 1
reach
"However, the amounts of TGF-beta1 were sufficient to consistently trigger Smad2 phosphorylation in fibroblasts."
TGFB1 phosphorylates SMAD2 on S467. 1 / 1
| 1
reach
"Phosphorylation of Smad2 at serine 465/467 (pSmad2) and Smad3 at serine 423/425 (pSmad3) by the activated TGFbeta1 receptor modulates their activity, allowing them to translocate to the nucleus and regulate TGFbeta1 target genes XREF_BIBR, XREF_BIBR."
TGFB1 phosphorylates SMAD2 on S465. 1 / 1
| 1
reach
"Phosphorylation of Smad2 at serine 465/467 (pSmad2) and Smad3 at serine 423/425 (pSmad3) by the activated TGFbeta1 receptor modulates their activity, allowing them to translocate to the nucleus and regulate TGFbeta1 target genes XREF_BIBR, XREF_BIBR."
TGFB1 phosphorylates SMAD2 on cysteine. 1 / 1
| 1
sparser
"Besides, in the TGF-β signaling pathway, TGF-β1 receptor kinases could phosphorylate Smad2 and Smad3 in the C terminal residue, resulting in forming a complex with Smad4, which plays the role of commo[MISSING/INVALID API KEY: limited to 200 char for Elsevier]"