IndraLab

Statements


USP34 affects NFIC
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USP34 deubiquitinates NFIC. 5 / 5
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"USP34 deubiquitinates and stabilizes NFIC."

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"Mechanically, we demonstrated that USP34 deubiquitinates and stabilizes NFIC during odontoblast differentiation."

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"To test whether USP34 dependent deubiquitination of NFIC is involved in odontogenic differentiation of DPCs, DPCs were infected with Lv-NFIC, or Lv-GFP as control."

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"XREF_BIBR, XREF_BIBR Our research identified that USP34 deubiquitinates and stabilizes NFIC to promote odontoblast differentiation and thus regulates root formation."

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"Ubiquitination assay showed increased ubiquitination level of NFIC in USP34 deficient 293T cells, indicating the presence of USP34 dependent deubiquitination of NFIC."
USP34 affects AXIN1
1 1 | 1
USP34 leads to the deubiquitination of AXIN1. 2 / 2
1 | 1

No evidence text available

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"USP34 reduced the ubiquitination of AXIN1, but the catalytic mutant of USP34 does not reduce the ubiquitination of AXIN1."
USP34 deubiquitinates AXIN1 on lysine. 1 / 1
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No evidence text available
USP34 affects RNF168
1 | 1
USP34 deubiquitinates RNF168. 2 / 2
1 | 1

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"A similar observation was seen when we immunoblotted immunoprecipitated RNF168 proteins with antibodies specific for lys48-ubiquitin linkages (XREF_FIG D), suggesting that USP34 may deubiquitylate and stablize RNF168."
USP34 affects AXIN2
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USP34 deubiquitinates AXIN2. 1 / 1
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No evidence text available
USP34 deubiquitinates AXIN2 on lysine. 1 / 1
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No evidence text available
USP34 affects CFTR
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USP34 deubiquitinates CFTR. 1 / 1
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"For example, in this and a previous study we observed that neither USP34, nor USP8 deubiquitinate CFTR, and only USP10 activity was inhibited by Cif XREF_BIBR, XREF_BIBR."
USP34 affects AXIN
| 1
USP34 deubiquitinates AXIN. 1 / 1
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"UBPY and USP8 positively regulates the pathway by modifying Frizzled (Mukai et al., 2010), whereas USP34 deubiquitinates Axin and consequently works as a negative regulator of the WNT pathway (Lui et [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"