IndraLab

Statements


SPARC affects ALE-0540
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SPARC activates ALE-0540. 1 / 1
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"PD90780, ALE-0540, Ro 08-2750, and PQC 083 were synthesized by Sussex Research (Ottawa, ON, Canada)."
ALE-0540 affects Pain
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ALE-0540 activates Pain. 1 / 1
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"ALE-0540 was tested in models of neuropathic pain and thermally-induced inflammatory pain, using two routes of administration, a systemic i.p."
ALE-0540 affects NGF
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ALE-0540 inhibits NGF. 1 / 1
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"We have identified a novel nonpeptidic molecule, ALE-0540, that inhibits the binding of NGF to tyrosine kinase (Trk) A or both p75 and TrkA (IC50 5.88 +/- 1."