IndraLab

Statements

IRF9 inhibits USP18.
| 2
IRF9 inhibits USP18. 2 / 2
| 2
reach
"Low dose IFNα increases baseline STAT2 and IRF9 expression without strongly activating the negative feedback regulators SOCS1, SOCS3, and USP18, thereby hypersensitizing cells to further interferon stimulation (26)."
35471841
reach
"The same procedure was performed for CRISPR based tagging the additional genes, STAT1, IRF9 and USP18 sequentially.The knockdown of USP18 by shRNA was done using retrovirus transduction."
32945770
IRF9 binds USP18.
| 1
USP18 binds IRF9. 1 / 1
| 1
sparser
"The coupled ISGF3-USP18 feedback system revealed in this study may function together with all the other mechanisms to maintain homeostasis in the responses to varying IFN signals."
32945770