IndraLab

Statements


CYLD binds TRAF3.
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| 1

sparser
"After initial details of the negative regulation of NF-kB by CYLD emerged, it was found that TRAF3, TRAF5 and TRAF6 do not interact with CYLD but a TRAF-interacting protein (TRIP) does [ xref , xref ]."
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sparser
"We have previously shown that mutations in CYLD and TRAF3 are associated with non-hyperdiploid karyotypes with a t(4;14)."
CYLD ubiquitinates TRAF3.
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CYLD leads to the ubiquitination of TRAF3. 1 / 1
| 1

reach
"Other DUBs that target the RIG-I and MDA5 pathway include CYLD and DUBA which target RIG-I and TRAF3 ubiquitination respectively (XREF_FIG)."