IndraLab

Statements

CYLD binds TRAF3.
| 1 3
CYLD binds TRAF3. 3 / 3
| 1 2
sparser
"We have previously shown that mutations in CYLD and TRAF3 are associated with non-hyperdiploid karyotypes with a t(4;14)."
30774775
reach
"The finding that all tumors with shallow co-occurring deletions in both TRAF3 and CYLD were included in the NF-κB “active” group suggests a functional interaction of TRAF3 and CYLD in these tumors."
35634245
sparser
"The finding that all tumors with shallow co-occurring deletions in both TRAF3 and CYLD were included in the NF-κB “active” group suggests a functional interaction of TRAF3 and CYLD in these tumors."
35634245
TRAF3 binds TRAF5, TRAF6, and CYLD. 1 / 1
| 1
sparser
"After initial details of the negative regulation of NF-kB by CYLD emerged, it was found that TRAF3, TRAF5 and TRAF6 do not interact with CYLD but a TRAF-interacting protein (TRIP) does [ xref , xref ]."
25342597
CYLD ubiquitinates TRAF3.
| 1
CYLD leads to the ubiquitination of TRAF3. 1 / 1
| 1
reach
"Other DUBs that target the RIG-I and MDA5 pathway include CYLD and DUBA which target RIG-I and TRAF3 ubiquitination respectively (XREF_FIG)."
22435550
CYLD deubiquitinates TRAF3.
| 1
CYLD deubiquitinates TRAF3. 1 / 1
| 1
reach
"For example, TNFAIP3, CYLD, USP3, USP4, USP15, USP25, and OTUD5 deubiquitinate key components of the IFN production pathway, including RIG-I, TRAF2, TRAF3, TRAF6, RIP1, and TRIF (reviewed in [93,94])."
38716888