IndraLab

Statements

reach
"A substantial reduction in viral load and more rapid virus elimination was seen in patients treated with a combination of hydroxychloroquine and azithromycin; however, the majority of patients treated with hydroxychloroquine alone continued to display symptoms of upper or lower respiratory tract infections [XREF_BIBR]."
32173235
reach
"He was continued on azithromycin and ceftriaxone and treated with hydroxychloroquine 400mg daily."
32304395
reach
"Results showed that the virus was not found after 6days in all the patients treated with HCQ and azithromycin, in 57.1% of the patients treated with HCQ only, and in 12.5% of the control group patients (p < 0.001)."
| PMC
reach
"Hydroxychloroquine (HCQ) decreases the benefit of anti-PD-1 immune checkpoint blockade in tumor immunotherapy.The anti-malarial 4-aminoquinoline drugs chloroquine (CQ) and hydroxychloroquine (HCQ) as well as the antibiotic azithromycin (AZ) have gained much attention as potential therapies."
34181666
reach
"14 A preexisting pro-inflammatory state, which is common to old age, obesity, tobacco abuse, infections, malignancies, autoimmune and cardiopulmonary disease, may be the common denominator that underlies susceptibility to cytokine storm and adverse outcomes in COVID-19 15 ; hence, the rationale to treat with immune/cytokine modulators such as chloroquine/hydroxychloroquine ± azithromycin, 16 tocilizumab, an IL-6 inhibitor, 17 anakinra, an IL-1β antagonist, and certolizumab pegol, an anti-TNF blocker."
| PMC
reach
"Out of 156 children, 78 (50%) children received Hydroxychloroquine containing regimen, 15 of them were treated with hydroxychloroquine + azithromycin + oseltamivir, 44 were treated with hydroxychloroquine + azithromycin and 21 were only treated with hydroxychloroquine."
33250495
reach
"Four patients were treated with azithromycin and a cephalosporin and two were also treated with hydroxychloroquine."
32469614
reach
"The reported effects of azithromycin are thus often derived from patients treated with hydroxychloroquine-azithromycin combination versus hydroxychloroquine alone."
33441373
reach
"On the other hand, HCQ was then added at a concentration of 6 μg/mL to each increased levels of DOXY i.e. 0.2, 2, 10, 100, and 400 μg/mL to produce HCQ 6 μg/mL + DOXY.Fig 9: The cytotoxicities of Favipiravir (FAVI) and Azithromycin (AZI) as a single drug (left) and dual drug combination in constant and non-constant ratios (right) analysed by using CompuSyn Software (n = 3)."
34143818
reach
"A small and poorly controlled French trial reported viral clearance at day 6 in 100% of COVID-19 patients treated with hydroxychloroquine and azithromycin, compared to 57% treated with hydroxychloroquine alone, and 13% in controls (Gautret et al."
32363726
reach
"The study revealed that at day 6 post-inclusion, 100% of the patients treated with the combination of hydroxychloroquine and azithromycin were cured, compared with 57.1% of the patients treated with hydroxychloroquine only, and 12.5% of the control patients."
33100439
reach
"On the sixth day from the beginning of treatment, all patients undergoing with hydroxychloroquine and azithromycin combination were clinically cured compared to 57.1% of patients treated with hydroxychloroquine alone."
32682787
reach
"They reported that the duration of hospital stay was higher in patients who were treated with both hydroxychloroquine and azithromycin compared to those who were only treated with hydroxychloroquine; but this difference was non significant (10.3 vs 9.6, Odds ratio :0.7, 95% CI : -0.6 -1.9) XREF_BIBR."
32853672
eidos
"A French paper reporting on the use of drug combinations in infected patients highlighted the possibility that hydroxychloroquine is effective in the treatment of COVID-19 patients [ 4 ] particularly in combination with azithromycin ."
32247925
reach
"It was found that about 100% of patients treated with Hydroxychloroquine in combination with Azithromycin were cured, while about 57.1% of patients treated with Hydroxychloroquine alone were cured XREF_BIBR."
| PMC