IndraLab

Statements

Heparin inhibits CTSL. 6 / 8
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"This contrasts with a recent study showing that heparin enhances the inhibition of cathepsin L by the “cross-class” serpin, squamous cell carcinoma antigen [43] ."
20230872
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"The presence of heparin accelerated inhibition of cathepsin L by both serpins, and in the case of SCCA-1, heparin increased the second order inhibition rate constant from 5.4 x 10 (5) to> 10 (8), indicating a rate enhancement of at least 180-fold."
19959474
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"For example, the glycosaminoglycan heparin, a known anti-coagulant, enhances inhibition of cathepsin L by serpin B3 and B4."
29632742
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"Clenbuterol and heparin weakly inhibit CatL and may have adjunctive value in the certain situations in COVID-19 disease."
32470470
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"More recently, it was reported that heparin accelerates the inhibition of cathepsin L by serpins due to the formation of ternary complexes with the enzyme and the inhibitor [35] ."
22234330
eidos
"Clenbuterol and heparin weakly inhibit CatL and may have adjunctive value in the certain situations in COVID-19 disease ."
32470470