IndraLab

Statements

Hydroxychloroquine inhibits IFN-I. 2 / 2
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"XREF_BIBR - XREF_BIBR Along those lines, hydroxychloroquine, documented to inhibit IFN-I production induced by lupus immune complexes in vitro, is now standard of care due to its demonstrated reduction of lupus flares."
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"The early blood IFN-I response was dependent on cGAS and was inhibited by hydroxychloroquine, which is consistent with our findings that aminoquinoline antimalarial drugs inhibit DNA activation of cGAS in vitro and in vivo XREF_BIBR, XREF_BIBR."
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