IndraLab

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CTNNB1 leads to the deacetylation of CTNNB1. 2 / 2
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"It was found that HIF-1alpha binds hARD1 through the oxygen dependent degradation domain and, in so doing, dissociates hARD1 from beta-catenin, which prevents beta-catenin acetylation."

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"Prior studies demonstrated that EGFR is an up-stream regulator of CTNNB1, inducing CTNNB1 deacetylation and nuclear localization in colon cancer cells."