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"Apart from this, we also predicted that hsa-miR-516a-3p down-regulates CTNNB1 gene, also known as beta-catenin, which is associated with WNT signalling for SCs renewal xref ."

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"Furthermore mutations in CTNNB1 , which encodes Beta-catenin are associated with increased Wnt signaling were identified in ∼ 20% of patients with hepatocellular carcinoma (HCC), including a patient with primary PFIC-2 diagnosis xref ."