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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified MTOR leads to the phosphorylation of EIF4EBP1. 2 / 2

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"Silencing Raptor or mTOR expression by RNAi equally decreases phosphorylation of S6K and 4EBP1, the direct downstream targets of mTORC1 XREF_BIBR."

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reach

"Importantly, expression of the mTOR AAA mutant in cells activated by amino acids severely diminished the phosphorylation of S6K and 4EBP1 (XREF_FIG) as well as the phosphorylation of a transfected S6K reporter construct (XREF_SUPPLEMENTARY)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...