IndraLab

Statements


TGFB bound to TGFBR2 activates SMAD3. 3 / 3
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"Binding of TGFβ to TGFBR1 and TGFBR2 leads to direct phosphorylation and activation of receptor-regulated SMAD (R-SMAD) proteins, SMAD2 and SMAD3."

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"The binding of TGF-β to its receptors TGFR1 and TGFR2 activates Smad2 and Smad3 through direct phosphorylation."

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"Binding of TGF-beta to TbetaR-II allows activation of TbetaR-I and leads to induction of the Smad2 and Smad3 signalling pathways."