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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

RAP1 binds BRAF and RAF1. 4 / 4

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"Using domain shuffling experiments, it was shown that the difference between Raf-1 and B-Raf appears to reside in the strength of interaction of Rap1 with the CRD domains of Raf-1 and B-Raf [61] ."

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"Although both B-Raf and Raf-1 bind to Rap1, only B-Raf is activated [41] ."

12074885

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"By contrast, the Rap1 works compared the interactions of Rap1 with Raf-1 with those of Rap1–BRAF and their consequences."

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"Thus, both Raf-1 and B-Raf are able to bind Rap1."

11730323

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

RAP1 binds BRAF and RAF1. 4 / 4

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