A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

MDM2 bound to CDKN2A increases the amount of TP53. 1 / 1
| 1
reach
"It is possible that small changes in p53 levels activated by PIM1 stabilization of the Mdm2 and ARF complex could be driving increases in transcription of p21, or, as our earlier work suggested, that other signaling pathways (i.e., PKC) possibly regulated by PIM1 could be playing a role in modulating p21 mRNA levels."