IndraLab

Statements

LRRK1 binds EGFR and GRB2. 7 / 7
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"LRRK1 forms a complex with activated EGFR via Grb2."
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"Interestingly, LRRK1 has been proposed to regulate endocytosis of EGFR via formation of a LRRK1, Grb2, and EGFR complex, while LRRK2 did not appear to form such a complex in this study suggesting that the two have functionally diverged."
25251388
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"Interestingly, LRRK1 has been proposed to regulate endocytosis of EGFR via formation of a LRRK1-Grb2-EGFR complex ( xref ), while LRRK2 did not appear to form such a complex in this study suggesting that the two have functionally diverged."
25251388
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"In this paper, we demonstrate that leucine-rich repeat kinase LRRK1, which contains a MAPKKK-like kinase domain, forms a complex with activated EGFR through an interaction with Grb2."
21245839
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"Our results demonstrate that LRRK1 forms a complex with EGFR via Grb2 and associates with STAM and Hrs in response to ligand stimulation."
21245839
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"We previously reported that LRRK1 forms a complex with activated EGFR through an interaction with Grb2 ( xref )."
22337768
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"We recently showed that LRRK1 forms a complex with activated EGFR through a mutual interaction with Grb2 ( xref )."
22337768