IndraLab

Statements


BRAF binds MAP2K1 and RAF1. 2 / 2
| 2

sparser
"Moreover, the overexpression of MEK1(3A) failed to block endogenous MEK1 activation, although MEK1(3A) formed complexes with both c-Raf and B-Raf as well as p42/p44 MAPK."

sparser
"When bound to trametinib, the dissociation constants for the interaction of MEK1 with either BRAF or CRAF kinase were 0.101 μM and 0.107 μM, respectively."