IndraLab

Statements

ZUP1 activates viral polymerase. 3 / 3
| 3
reach
"We also reported that the TYMV papain-like cysteine PRO domain involved in the proteolytic processing of the viral replication precursor protein [29–31], also displays a DUB activity that was able to rescue the viral polymerase from degradation [32]."
29117247
reach
"Interestingly, the CCHFV OTU protease comprises a domain on the viral polymerase, and targeting it with a UbV may not only suppress viral pathogenicity but RNA replication as well, since it has been found that viral OTU DUB activity can suppress proteasome-dependent viral polymerase degradation [43]."
28542609
reach
"We also reported that the TYMV papain-like cysteine PRO domain involved in the proteolytic processing of the viral replication precursor protein [29] [30] [31] , also displays a DUB activity that was able to rescue the viral polymerase from degradation [32] ."
29117247