IndraLab

Statements


Peroxynitrite decreases the amount of IRS1. 2 / 2
| 2

reach
"Our results suggest that peroxynitrite reduces the IRS-1 protein level and decreases phosphorylation of IRS-1 concurrent with nitration of its tyrosine residues."

reach
"Thus, peroxynitrite reduces the level of IRS-1, while inducing at the same time its tyrosine nitration, thereby impairing insulin signalling on Akt and PKB."