IndraLab

Statements


ST3GAL4 decreases the amount of IRS1. 3 / 3
| 3

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"In contrast, i.c. STZ inhibition of IRS-1 protein expression was abrogated by both early and delayed administration of T3D-959 (XREF_FIG)."

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"QPCR demonstrated that STZ decreased expression of IR and IRS1 mRNA."

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"i.c. STZ treatments caused neurodegeneration with increased pTau, AbetaPP, Abeta 42, ubiquitin, and SNAP-25, and reduced levels of synaptophysin, IGF-1 receptor (R), IRS-1, Akt, p70S6K, mTOR, and S9 -GSK-3beta."