Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified PTEN leads to the phosphorylation of IRS1 on S307. 1 / 1

| 1

➶

reach

"A recent study identified that HCV infection may lower the expression of phosphatase and tensin homolog deleted on chromosome 10 (PTEN), which in turn increases phosphorylation of IRS1 at Ser307 and inhibits the PI3K and Akt signaling pathway, leading to insulin resistance."

27432476

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...