IndraLab

Statements


BRAF phosphorylates MAP2K1 on S222. 14 / 14
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"B-Raf phosphorylates MEK1 and MEK2 on Ser217 and Ser221, which activates it to dual phosphorylate ERKs, at Thr202/Tyr204 for human ERK1 and Thr185/Tyr187 for human ERK2 [ xref , xref ]."

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"B-Raf phosphorylates MEK1 and MEK2 on Ser217 and Ser221, which activates it to dual phosphorylate ERKs, at Thr202 and Tyr204 for human ERK1 and Thr185 and Tyr187 for human ERK2 [XREF_BIBR, XREF_BIBR]."

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"Raf-1 phosphorylation of MEK activated it, as judged by its ability to stimulate the phosphorylation of myelin basic protein by glutathione S-transferase-ERK1."

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