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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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KRAS-G12D activates MAPK1. 3 / 3

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"Further molecular studies elicited that Kras G12D activated ERK2 and enhanced the invasion of pancreatic cancer cells via MMP-1 [XREF_BIBR]."

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"Constitutive K-Ras G12D Activation of ERK2 Specifically Regulates 3D Invasion of Human Pancreatic Cancer Cells via MMP-1."

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"Specifically, the constitutive activation of ERK2 by K-Ras G12D is necessary for the upregulation of MMP-1 RNA, its secreted protein, and its proteolytic activity."

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KRAS-G12D activates MAPK1. 3 / 3

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