IndraLab

Statements


CTNNB1 bound to MUC1-C activates CTNNB1. 2 / 2
| 2

reach
"The functional significance of the MUC1-C and beta-catenin interaction is supported by the demonstration that MUC1-C stabilizes beta-catenin by blocking GSK3beta mediated phosphorylation of beta-catenin and thereby its proteosomal degradation."

reach
"In contrast to the DKK mechanism, MUC1-C binds directly to and stabilizes beta-catenin, and thereby activates WNT and beta-catenin signaling."