IndraLab

Statements

Modified EGFR increases the amount of EGFR. 9 / 9
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"In this study we show that transient or stable overexpression of the EGFR predictably leads to ligand dependent apoptosis in a variety of cell lines suggesting that apoptosis may be a general outcome [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
11226409
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"EGFR surface expression increased 4-fold and 6-fold on BM KSL and SLAM + KSL cells, respectively, at 4 hours following 300 cGy irradiation, demonstrating induction of EGFR expression on HSCs following irradiation (XREF_FIG)."
23377280
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"Expression of EGFR (XREF_FIG), but not FSHR (XREF_FIG), after pre-IVM for 2 h was increased by the combination of dbcAMP and IBMX, but not by dbcAMP or IBMX alone (P < 0.05), suggesting a possible regulation of EGFR expression by cAMP."
29503399
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"Importantly, the ligand OSM regulates EGFR phosphorylation in wild type mouse astrocytes, and knockdown of OSMR in EGFRvIII expressing astrocytes reduces the phosphorylation and total levels of EGFRvIII."
28177884
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"However, further overexpression of EGFR on a background of Cbl-b overexpression can relieve Cbl-b-mediated EGFR degradation and restore EGFR expression, mesenchymal phenotype, and cell migration capacity in MDR gastric and breast cancer cells."
28334634
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"Transient expression of constitutively active EGFR (EGFR L858R) (Uchida et al., 2007) restored hBD3 mRNA expression 24 hr p.i., as did overexpression of WT EGFR."
22704618
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"In addition, the reduced levels of EGFR leads to decreased EGFR phosphorylation levels at Y992 and T1068, and decreased phosphorylation of EGFR also elicits reduction of several downstream kinase pathways."
24625091
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"Overexpression of EGFR on a background of Cbl-b overexpression restored EGFR expression and facilitated activation of EGFR and ERK and Akt compared with Cbl-b overexpression alone (XREF_FIG A)."
28334634
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"Expression of wild-type EGFR and mutant EGFR receptors increased p-EGFR levels compared with vector control or mutant K-ras retrovirus infected cells."
22634180