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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

EGF binds EGFR and RET. 2 / 2

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"On further investigation, we demonstrated an EGF induced interaction between EGFR and RET that was abrogated by both EGFR and RET inhibitors, but to differing degrees in the three cell lines, potentially stemming from differences in the origins of the cell line models and their individualized neoplastic properties from the mutation profiles in each tumor model."

28460442

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sparser

"RET and EGFR interact only in the presence of EGF and predominantly through the long RET isoform."

28460442

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...