IndraLab

Statements


Modified MDM2 leads to the phosphorylation of TP53. 1 / 1
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reach
"In addition, cytoplasmic localization of T155E is further enhanced by Hdm2 overexpression, implying that Hdm2 mediated mono-ubiquitination of p53 and Jab1 mediated p53 phosphorylation cooperatively increases the interaction between CRM1 and p53, which ultimately facilitates nuclear export of p53."