IndraLab

Statements

CC.4 inhibits ZUP1. 2 / 2
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reach
"Slopes of linear portions of fluorescent signal formation were used to determine the velocity of substrate cleavage in the presence and absence of ubiquitin variant CC.4 (CC.4) which has been shown previously to inhibit DUB activity of CCHFV isolated OTU-domain [27]."
32497085
eidos
"DUB activity velocities were plotted versus CC.4 concentrations and fitted to a log ( inhibitor ) - versus-normalized-response - ( variable slope ) equation using GraphPad Prism 7.0 ( GraphPad Software , Inc ., San Diego , CA , USA ) to determine the IC50 values for the inhibition of DUB activity by CC.4 ."
32497085