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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

BRAF binds RAF1 and rluC. 3 / 3

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"Using transfection conditions that yielded low, medium, and near saturating levels of V-BRAF WT :RLuc-CRAF interaction, we measured MEK phosphorylation."

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"Upstream stimulation only modestly induced an interaction between a V-BRAF R188L mutant and RLuc-CRAF."

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"We determined transfection conditions in HEK293T cells where formation of V-BRAF V600E :RLuc-CRAF dimers was induced by co-expression with NRAS Q61K as a constitutively active surrogate for pathway stimulation (STIM)."

28947418

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Statements

BRAF binds RAF1 and rluC. 3 / 3

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