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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

ERK binds CDC42, MAP2K1, PAK1, PAK3, RAC1, and RAF1. 1 / 1

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"These findings may be explained by the previous findings that Rac1 and Cdc42 can interact with Raf-1 in a synergistic manner to activate ERK via pathways that involve phosphorylation of both MEK1 by PAK1 and Raf-1 by PAK-3 [ xref , xref ]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...