IndraLab

Statements


Modified CTNNB1 leads to the dephosphorylation of CTNNB1. 2 / 2
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"More important, beta-catenin expression was down-regulated but phosphorylated beta-catenin expression and phosphorylated GSK-3beta expression was up-regulated upon Nanog overexpression."

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"Functional studies showed that the activation of NF-kappaB transcriptional activity in mutant osteoblasts resulted in increased beta-catenin phosphorylation, reduced osteoblast beta-catenin expression, and altered expression of Wnt and beta-catenin target genes."