IndraLab

Statements

TSC1 binds TSC1, TSC2, and TSC2. 5 / 5
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sparser
"It is also possible that TSC1 facilitates the formation of TSC1-TSC2 complexes containing multiple TSC1 and TSC2 subunits."
23006675
sparser
"Therefore, it is unlikely that the detected TSC1–TSC1 interactions are a consequence of the formation of TSC1–TSC2 complexes containing multiple TSC1 and TSC2 subunits."
20547222
sparser
"TSC is a dominantly inherited multisystem disorder characterized by the formation of hamartomas in different organs and the brain, caused by mutations in the TSC1 or TSC2 genes encoding hamartin and tuberin, respectively."
30705255
sparser
"TSC1 and TSC2 interact to form large complexes containing multiple TSC1 and TSC2 subunits."
23006675
sparser
"Hamartin and tuberin, the TSC1 and TSC2 gene products, interact and the tuberin-hamartin complex inhibits cell growth by antagonising signal transduction to downstream effectors of the mammalian target of rapamycin (mTOR) through the small GTPase rheb."
15483652